Effects of high-fat diet on growth and depression-like behavior of prenatal stress offspring rats

To investigate effects of high-fat diet (HFD) on body length, weight and depression-like behavior prenatal stress (PS) offspring rats. PS rat model was established by restraint stress. Sucrose preference forced swimming tests were performed. Moreover, the HFD growth in rats observed. Length male female HF group significantly longer than that control, but length PS+HF shorter group. Body higher lower No significant differences observed between +HF groups. Compared with group, rate higher. could reduce sucrose preference, prolong immobility time can promote gain normal partially inhibit rats, exert no aggravate PS-induced